Impact profenophos (pesticide) on infectivity of Biomphalaria alexandrina snails with schistosoma mansoni miracidiaand on their physiological parameters

Profenophos is an organophosphorus pesticide which are used effectively against cotton insects and mites.The present work was carried out to evaluate the molluscicidal activity of pesticides (Profenophos) against Biomphalaria alexandrina snails. Also, the effect of sublethal concentrations of pesticide on the infection of B. alexandrina with Schistosoma mansoni and some enzymes of energy metabolism were studied. The results showed that the infection of B. alexandrina with schistosoma mansoni was greatly reduced after exposure to LC0, LC10, LC25 of pesticide and also, reduction in number of cercariae per snail during the patent period and in the period of cercarial shedding. The present study indicated that the increase in levels of aminotransaminases, acid phosphate-se and alkaline phosphatases enzymes in haemolymph and soft tissue of snails and the activity level of lactate dehydrogenase, hexoki-inase and pyruvatekinase was also significantly reduced in response to treatment.